Factors in the Genetic Background Suppress theEngrailed-1Cerebellar Phenotype
نویسندگان
چکیده
منابع مشابه
Factors in the genetic background suppress the engrailed-1 cerebellar phenotype.
The mouse homeodomain protein, Engrailed-1, is generally viewed as an essential player in the early establishment and maintenance of the midbrain/hindbrain region that gives rise to the cerebellum and midbrain. In keeping with this, engineered null mutations at this locus have been reported to lead to perinatal lethality accompanied by near-total absence of cerebellar and caudal midbrain struct...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2003
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.23-12-05105.2003